Two nutrients that are critical for optimal endothelial function and structural integrity

60 capsules , #881, $57.95

The endothelium is the thin barrier that separates circulating blood from the smooth muscle interior of the artery. Healthy endothelial cells help to maintain a normal cardiovascular system. Aging, poor lifestyle habits and nutrition can lead to endothelial problems which can lead to fatigue, atherosclerosis, blood pressure problems and other vascular disorders.

Propionyl-L-Carnitine (PLC) plays an important role in protecting the function and health of endothelial cells.1-3 PLC passes across the mitochondrial membrane to supply carnitine directly to the energy-producing organelles of all cells. Carnitine is essential for mitochondrial fatty acid transport and energy production. This is important because endothelial cells burn fatty acids for 70 percent of their energy.4

Adenosine triphosphate (ATP) is a critical component of the cellular energy cycle. When administered orally to rabbits, ATP increased blood flow, reduced vascular resistance, and increased arterial oxygen pressure.5 In baboons, ATP infusions increased cerebral blood flow by nearly 50 percent and boosted oxygen consumption in the brain.6

Peak ATP™ is a patented brand of ATP that has been tested in human and animal studies. Peak ATP™ is readily absorbed and boosts circulating ATP levels.7-9 Red blood cells release ATP to produce endothelial vasodilation, or widening of the arteries. Ensuring adequate red blood cell pools of ATP to help regulate vascular tone is critical to maintaining circulatory health.10

For the first time, Americans have access to proprionyl-L-carnitine and Peak ATP™, two nutrients that are critical for optimal endothelial function and structural integrity .

References
1. Available at http://www.infoplease.com/ipa/A0779147.html. Accessed July 26, 2005.
2. Rubanyi GM. The role of endothelium in cardiovascular homeostasis and diseases. J Cardiovasc Pharmacol. 1993;22 Suppl 4:S1-14.
3. Available at http://www.medreviews.com/pdfs/articles/RIU_5Suppl7_S21.pdf. Accessed July 25, 2005.
4. Kaiser KP, Feinendegen LE. Planar scintigraphy versus PET in measuring fatty acid metabolism of the heart. Herz. 1987 Feb;12(1):41- 5. Kichenin K, Seman M. Cronic oral administration of ATP modulates nucleoside transport and purine metabolism in rats. J Pharmacol Exp Ther. 2000 July;294(1):126-33.
6. Van Aken H, Puchstein C, Fitch W, Graham DI. Haemodynamic and cerebral effects of ATP-induced hypotension. Br J Anaesth. 1984 Dec;56(12):1409-16.
7. Kichenin K, Decollogne S, Angignard J, Seman M, Cardiovascular and pulmonary response to oral administration of ATP in rabbits. J Appl Physiol. 2000 Jun;33(6):1962-8..
9. US patent 5,049,372. US patent 5,227,371.
10. Ellsworth ML, Forrester T, Elias CG, Dietrich HH. The erythrocyte as a regulator of vascular tone. Am J Physiol 1995 Dec;269 (6 Pt 2):H2155-61.

Supplement Facts
Serving Size 1 enteric-coated capsule
Servings Per Container 60

Amount Per Serving
GlycoCarn™ Glycine...........500 mg
Propionyl-L-Carnitine Hydrochloride

PEAK ATP™......................100 mg
Adenosine 5'-Triphosphate Disodium

Other ingredients: vegetable cellulose, rice powder, silica and magnesium stearate.

Enteric coating consists of methacrylic acid copolymer, myvacet, triacetin and polysorbate 80.

PEAK ATP™ is a trademark of Technical Sourcing International, Inc. and is protected by U.S. Patent Nos. 5,227,371 and 5,049,372 and other patents pending. GlycoCarn™ is a trademark of Sigma-tau HealthScience, Inc. and is protected by U.S. patent No. 6,703,042 B1.

Dosage and Use
Take one capsule twice daily on an empty stomach.

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