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Yeast Infection Protocol

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YEAST FIGHTERS



Candidiasis is an infection caused by various species of the Candida yeast, the most common being Candida albicans. Candida are normally present in the digestive tract and the vagina. During certain favorable conditions, such as warm, humid weather or when an individual's immune system is impaired, the yeast can infect the skin. Mucous membranes in the mouth and vagina are commonly infected. In rare instances, Candida can invade blood and deeper tissues, causing a life-threatening infection.

People may sometimes develop a Candida infection after taking antibiotics (Still et al. 1995; Witsell et al. 1995). The antibiotics kill the bacteria that normally keep the Candida under control, allowing the Candida organism to grow unchecked. Pregnant women, diabetics, and obese people are also prone to Candida infections. Corticosteroids given after organ transplantation can also promote growth of Candida.


COMMONLY INFECTED AREAS

Skin folds, including the navel and anus. Symptoms include a red rash with patchy areas oozing whitish fluid. Pus may also appear. The area will itch or burn. Perlèche is a Candida infection at the corners of the mouth that creates cracks and tiny cuts. It is often caused by ill-fitting dentures.
Vagina (vulvovaginitis), occurring most often in pregnant women, those taking antibiotics, or those with diabetes. Symptoms include a white or yellow discharge, with burning, itching, and redness on the walls and the external areas of the vagina.
Penis, occurring mostly in men having diabetes or whose sexual partner has a vaginal Candida infection. A red, scaly, often painful rash appears on the underside of the penis. However, a fungal infection of the penis (or vagina) will not always cause discernible symptoms.
Mouth (thrush), (caused by a candida infection in the mouth) where creamy white patches will appear on the tongue or sides of the mouth. Thrush can appear in a healthy child; however, in an adult it may be a symptom of a more serious disorder, such as diabetes or AIDS. The use of antibiotics can also cause thrush.
Nails (paronychia), (caused by a candida infection in the nail bed) resulting in a painful swelling and secretion of pus from the nail beds. Infected nails may turn white or yellow and separate from the surrounding skin.

CANDIDIASIS AND THE YEAST SYNDROME

Most conventional physicians restrict a diagnosis of candidial infection to the previously mentioned conditions. When there is doubt, cultures may be obtained to prove the diagnosis and to check for susceptibility to antifungal agents. Conventional physicians may also encounter the particularly vexing problem of women who have multiple vaginal yeast infections that are difficult to control. Many of these women are treated with repeated courses of potent antifungal drugs, often without relief.

Another more controversial perspective was popularized by Dr. W. G. Crook (1986, 1999). Dr. Crook used the term "candidiasis" or "yeast syndrome" to refer to a syndrome in which the predominant features are fatigue, a generalized malaise, gastrointestinal complaints, recurrent chronic infections, allergies, skin problems, decreased concentration, depression, irritability, and craving for sweets or carbohydrates. The underlying cause is purported to be an overabundance of yeast in the bowel and perhaps elsewhere. While this theory has not been investigated and subjected to the rigorous scrutiny of peer review, there is certainly substantial clinical and anecdotal evidence that this syndrome exists and appears to be connected with the overuse of antibiotics. Many patients who have been diagnosed with yeast syndrome do get better when they follow a diet essentially devoid of sugar, yeast-containing substances, and wheat.

If you utilize the questionnaire following this protocol, which comes from Dr. Crook, you may better understand the problem. Physicians experienced with this condition can also look for Candida antibody levels in the blood and do an ELISA-ACT test for T-cell mediated allergy. (See the Allergies protocol for a discussion of this very useful test.) It is also useful to check the acidity of the stomach and the alkalinity of the first part of the duodenum with a Heidelburg test. This is a noninvasive test utilizing a small capsule, containing a sensitive pH probe and radio transmitter, that is swallowed by the patient. A radio receiver picks up the signals and measures the perspective values. The capsule passes harmlessly into the test probe afterlife. Abnormalities of stomach and pancreatic secretions can be corrected with the proper supplements.


TREATMENT

Sugar
Probiotics
Yeast Fighters
Antifungal Drugs
Treatment of Candida depends upon the location of the infection. Infection of the skin is easily treated with medicated creams and lotions, often containing nystatin. Suppositories may be used for vaginal and anal infection. Thrush medications may be taken as a liquid swished around the mouth or as a slowly dissolving lozenge. Along with an antifungal cream, hydrocortisone for skin infection may be used to relieve pain and itching. Keeping the skin dry will help to clear up the infection and prevent its return.

Most people have a bout with a candidial infection at one time or another in their lives. This discussion is directed to the patients that either have recurrent infections or suffer from yeast syndrome. It is very important to screen for the more obvious and common predisposing factors like diabetes or chronic steroid use. The challenge is to look for more subtle problems that impair immunity. One must realize that there is a vicious cycle, especially in yeast syndrome. A person may become predisposed to a yeast infection because of antibiotic overuse. Then when the syndrome takes hold, immune function is further impaired, making it all the more difficult to treat. Therefore, based on the clinical experience of many physicians, it is fair to say that anyone suffering from either recurrent yeast infections or the yeast syndrome should adhere to most of the suggestions that follow, especially with respect to dietary changes.


Removal of Sugar
The importance of the removal of sugar from the diet cannot be overemphasized. For reasons that are not entirely clear, many patients suffering from this problem have serious sugar and carbohydrate cravings that are of an addictive nature. There is no magic bullet. Failure to change the diet will result in failure to recover from the problem. Anyone who tells you that you can merely take an antifungal drug to cure the problem is mistaken! If ELISA-ACT testing reveals food allergies, those foods need to be avoided during the recovery period.

Some authorities suggest that decreasing honey and fruit juice during the period of recovery is sufficient. Many physicians feel that people may need to eliminate these foods entirely during the recovery period and reintroduce them slowly following recovery. The same may be said for dairy products. Yeast-containing products are a definite no. The reader is referred to Dr. Crook (1986, 1999) for an exhaustive description of the proper diet. In addition, as mentioned, consideration should be given to supplemental hydrochloric acid and pancreatic enzymes if indicated.

Many readers are probably thinking "how long must I stay on this diet?" The truth is that as far as sugar is concerned, one should never resume its use. The other foods may often be reintroduced slowly. Again, it is wise to work with a physician experienced with recurrent yeast infections. It may also be said that as a person gets more attuned to their body's health a certain sensitivity develops letting one know that eating certain things leaves one feeling "not right." This question is the same as when a patient asks how long they should avoid using an injured limb. The answer, of course, is "when it no longer hurts!" Your body knows what is right and wrong for it. It always knew. One just has to relearn by self-observation.

Often a person will report that after following this diet for 2 to 4 weeks they begin to feel worse. This is most probably a result of the yeast dying off and releasing toxins. It is for this reason that the diet should include plenty of fiber to ensure proper elimination. Additionally, 2-4 weeks of a proper diet should be undertaken before initiating treatment with antifungal agents, natural or otherwise.


Probiotics
Natural agents are frequently neglected for the treatment and prevention of selected intestinal and vaginal infections. Placebo-controlled studies demonstrated that natural agents have been used successfully to prevent antibiotic-associated bacterial infections and Candida vaginitis (Collins 1980). Few adverse effects have been reported. There is now significant evidence that administration of selected microorganisms is beneficial in the prevention and treatment of certain intestinal infections, and possibly in the treatment of vaginal infections (Jack et al. 1990; Elmer et al. 1996). These are called probiotics and are particularly useful in treating yeast syndrome.

The intake of bifido bacteria concentrate capsules every day can dramatically increase the quantity of beneficial bacteria in the gut to help fight Candida infections. Acidophilus bacteria also can help to fight Candida in the upper intestinal tract. Bifido bacteria (a beneficial bacteria located in the lower intestines) feed on a special sugar called fructo-oligosaccharides found in a product called NutraFlora. One teaspoon (4 grams) a day of fructo-oligosaccharide promotes the proliferation of friendly bifido bacteria in the gut (Howard et al. 1995; Oyarzabal et al. 1995; Buddington et al. 1996).

Studies have shown that the daily ingestion of 150 mL of yogurt enriched with live Lactobacillus acidophilus is associated with an increased colonization of friendly bacteria in the rectum and vagina (Shalev et al. 1996). This results in reduced episodes of bacterial vaginitis. Yogurt is often used by women with chronic vaginal Candida infections (Hilton 1992). This should not be used for treating yeast syndrome or for those with known milk sensitivity.


Natural Yeast Fighters
Garlic, biotin, and caprylic acid have a direct yeast-killing effect in the intestine (Dausch 1990). Fiber in the diet also can help remove yeast and fungus from the intestines. A product called Yeast Fighters, made by Twin Lab, contains an odorless garlic concentrate, caprylic acid, biotin, Acidophilus sp, and a fiber blend to control Candida overgrowth in the intestine before it spreads to other parts of the body.

Other supplements to consider are goldenseal (Hydrastis canadensis) and volatile oil from oregano (Hammer et al. 1999). Both have antifungal properties. Goldenseal is probably best taken as an infusion such as in a tea bag or about 4 grams, 3 times a day in capsule form. Oregano oil comes in an enteric-coated capsule to protect you from a bad bout of dyspepsia (heartburn.) Take 1 capsule on an empty stomach 3 times a day.

A possibility for treating a yeast infection is a subfraction of whey protein called lactoferrin. Several studies have found lactoferrin to inhibit a wide range of gram positive and gram negative bacteria, yeasts, and even certain intestinal parasites. C albicans, in particular, has been proven to be inhibited by lactoferrin (Percival, 1997; Kuwata et al., 1998). One to two capsules of lactoferrin should be taken daily, with or without meals.

Although research has not yet proven orthomolecular therapies to be useful for this, some physicians who practice complementary therapies administer nutritional intravenous vitamins, particularly vitamin C, during the recovery period (Wu et al. 1998). Clinically, patients seem to feel stronger more quickly when this is done.

Studies have demonstrated the antifungal properties of tea tree oil (Melaleuca alternifolia) against a wide range of fungal isolates including species of Candida (Hammer et al. 1997; Rushton et al. 1997). Studies indicate that controlled doses of tea tree oil may be used as an effective topical treatment for dermatologic Candida infection and paronychia.

Shark liver oil has demonstrated an antifungal effect in laboratory studies. Shark liver oil capsules containing 200 mg of alkyl glycerol can be taken in doses of 5 capsules a day for up to 30 days. After 30 days, reduce the dose to 2 capsules a day or stop altogether. Shark liver oil promotes the healthy production of blood cells, particularly platelets .

Note: If you have been diagnosed with thrombocytosis (too many platelets), then do not take shark liver oil supplements.


Antifungal Drugs
When diet and "natural" therapies fail, a number of antifungal drugs can be considered. One is nystatin, which works only in the bowel and is not absorbed systemically. The dosage is variable and is usually given mixed in water. Infection of the skin is easily treated with medicated creams and lotions containing nystatin. Suppositories may be used for vaginal and anal infection. Thrush medications may be taken as a liquid swished around the mouth or as a slowly dissolving lozenge.

The other drug, Diflucan, is the most potent FDA-approved antifungal drug available. One month's treatment with Diflucan can temporarily eradicate a systemic Candida infection (Dmitrieva et al. 1993) so that anti-Candida nutritional supplements like Yeast Fighters, Life Flora (bifido bacteria), and NutraFlora (fructo-oligosaccharides) can prevent a new Candida infection from occurring.

Along with an antifungal cream, hydrocortisone for skin infection may be used to relieve pain and itching. Keeping the skin dry will help to clear up the infection and prevent its return.


SUMMARY

Investigate carefully for underlying health problems.
For one-time infection, use traditional local treatment with a topical antifungal or systemic treatment with Diflucan to eradicate the primary yeast infestation.
Follow the yeast syndrome diet for 2-4 weeks prior to initiating antifungal therapy, but probiotics (see #4) may be initiated during this time.
Take probiotics with Lactobacillus acidophilus and Lactobacillus bifidum, such as Life Flora (1 tsp a day up to 3 times a day) or Primal Defense (1 capsule 3 times daily).
Consider ELISA-ACT allergy testing.
Consider Heidelberg testing for gastrointestinal secretions.
Use HCl and/or pancreatic enzymes if indicated.
Consider Yeast Fighters containing garlic, biotin, and caprylic acid, 5 capsules daily.
Consider goldenseal infusion, or about 4 grams in capsule form, taken 3 times a day.
Consider oregano oil, enterically coated. One 400-mg softgel twice daily with a small amount of warm water between meals is recommended.
Consider shark oil, up to 5 capsules a day for no more than 30 consecutive days. After 30 days, reduce the dose to 2 capsules a day or stop altogether. Each capsule should contain 200 mg of alkyl glycerol. Shark liver oil promotes the healthy production of blood cells, particularly platelets. Note: if you have been diagnosed with thrombocytosis (too many platelets), then do not take shark liver oil supplements.
Consider lactoferrin, 300-600 mg a day with or without food.
Consider orthomolecular therapy with intravenous vitamins, in particular vitamin C, 50 grams IV, 1-3 times a week.
Please note that studies have not been done to ascertain exact dosing. It is also unclear whether to combine the antifungals or use them one at a time. It is probably best to begin with single agents and add others if necessary.
Refer to the Obesity protocol for information about cutting carbohydrate (sugar) craving.
For more information

Contact the National Women's Health Network, (202) 628-7814. A staffer will answer questions on vaginitis and yeast infections. An information packet costs $6 for members and $8 for nonmembers. Also refer to Crook (1986, 1999).

 

 

 

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