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Three Double-Blind Placebo-Controlled
Studies Human growth hormone (hGH) receives a good deal of public attention for the ability to build lean body mass, increase physical performance, enhance immune function, and improve body composition and shape.(1-7) Lean body mass includes muscle, bone, and organ density, i.e., the body's fat-free mass. Maintenance of lean body mass extends life, because muscle weakness, organ failure, and death are direct results of lost lean body mass.(8, 9) In one study, men, ages 61-80 years old, who injected pharmacologic concentrations of 50 mg of recombinant hGH 3 times per week for 6 months improved in health achieving a state that is more similar to a youthful state by raising lean body mass by 8 percent, decreasing fat by 14 percent, increasing spleen and liver sizes by 18 percent, and increasing bone density.(10) Other clinical studies on adults with growth-hormone deficiency (GHD) found that hGH replacement therapy improved subjects' body composition and quality of life.(3-5, 11, 12) Problems Associated with Too Much or Too Little hGH The American Association of Clinical Endocrinology defines GHD as a cluster of self-perceived symptoms as listed in Table 1. Age-related declines in hGH and insulin-like growth factor (IGF)-1 levels are also used to define GHD. Following puberty, hGH declines exponentially.(13) Growth-hormone (GH) secretion peaks at 31 years of age, then declines by 14-50 percent per dectension. In acromegaly, the most striking problems are enlargement of the heart, lungs, liver, thymus, and spleen. Hyperthyroidism may result in addition to hyperglycemia and glucosuria. Finally, overgrowth of the bones in the face, hands, and feet occur. The jaw protrudes and becomes massive, with thick lips and an overly large tongue, and there is accentuation of the orbital and frontal ridges. The adrenal, thyroid, and parathyroid glands hypertrophy or overgrow. TABLE 1.
The most notable abnormality caused by excess hGH is early hypersexual drive followed by gonadal atrophy, impotence, and amenorrhea. Positive and negative effects of hGH highlight the body's complex feedback mechanisms, which respond to various time dependent and environmental conditions to achieve homeostasis. It may be possible to develop a new, nontoxic, delivery for hGH as an over-the-counter medicine to address the self-diagnosed symptoms of GHD during the aging process. Oral supplementation with Hormone-Therapy hGH necessitates systematic evaluation for efficacy. In clinical practice, Hormone-Therapy drugs have demonstrated effectiveness repeatedly, (22-24) bringing the body closer to homeostasis.(25)
Some Homeopathy Basics Homeopathy uses drugs that have been highly diluted to produce safe, less expensive, and nontoxic medicines. Injectable recombinant hGH is expensive, often costing $1,000 or more per month. Samuel Hahnemann, M.D., the founder of homeopathy, developed the well-known Law of Similars after years of observing the interactions between drugs and the body.26He identified two elements underlying the fundamental principle of pharmacology, i.e., a drug has a physiologic effect on the body and the body reacts positively and negatively to a drug, producing symptoms. Dr. Hahnemann found that, by serially diluting drugs into Hormone-Therapy preparations, he could induce patients to experience key positive attributes of drugs without having their associated negative reactions. The first systematic study of drug action was the Hormone-Therapy practice of "proving" potential medicines on healthy volunteers.(27) Typically, a Hormone-Therapy drug proving includes assessment of the drug's action on healthy subjects at concentrations high enough to produce or alleviate symptoms in sensitive individuals. Data collected from self perceived symptoms on verum (treatment) versus placebo are compared to determine each drug's guiding symptoms and characteristics. The Three Studies We evaluated the efficacy of Hormone-Therapy recombinant human growth hormone (HhGH) in three different double-blind placebo-controlled studies. First, we evaluated if there was statistical significance between treatment and placebo; second, we evaluated different treatment effects based on the concentration of treatment. Our results suggest that HhGH provides a safe, affordable, statistically significant method of improving body composition and shape, in terms of increasing upper-arm size, decreasing hip size, and increasing chest size. We also demonstrated improved self-perceived quality-of-life parameters over the placebo effect.
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These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease
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